1. The Effect of Combined Steroid and Calcium Channel Blocker Injection ...
Comparison of Steroid and Botulinum Toxin Type A Monotherapy with Combination Therapy for Treating Human Hypertrophic Scars in an Animal Model · Medicine.
The first evidence of verapamil‐augmented decorin expression spatially correlated with collagen bundles in HScs is presented, demonstrating equal or better efficacy than monotherapy, reducing the side effects of a single drug. BACKGROUND Hypertrophic scars (HScs) are inelastic scars that can cause functional loss and disfigurement. Decorin regulates collagen fibrillogenesis, and its expression is lower in HScs than in normal skin and during wound healing. OBJECTIVE To evaluate the efficacy of combined verapamil and triamcinolone in treating HScs. METHODS Excised human HSc fragments from surgically treated burned patients were divided into three groups: A (normal saline), B (verapamil), and C (verapamil and triamcinolone). The specimens were bilaterally implanted in the back of nude mice, treated using intralesional injections, and observed for 4 weeks. We compared the fibroblast viability and proliferation, decorin staining, and scar weights to evaluate treatment efficacy. RESULTS Viability and proliferation of HSc fibroblasts from groups B and C were significantly lower at all time intervals after transplantation (p<.001). Treatment (Groups B and C) stimulated strong decorin staining by 4 weeks. Nonsignificant differences in changes in scar weight were observed between groups. CONCLUSIONS We present the first evidence of verapamil‐augmented decorin expression spatially correlated with collagen bundles in HScs. Combination therapy can reduce the dosage of each drug but achiev...
2. Mechanotransduction in skin wound healing and scar formation - Frontiers
Recent studies indicate that mechanical force significantly impacts wound healing and skin regeneration which opens up a new direction to combat scarring.
Hypertrophic scarring (HTS) is a major source of morbidity after cutaneous injury. Recent studies indicate that mechanical force significantly impacts wound ...
3. Multi-Depth Boundary-Aware Left Atrial Scar Segmentation Network
8 aug 2022 · In this work, we propose a boundary-aware LA scar segmentation network, which is composed of two branches to segment LA and LA scars, respectively.
Automatic segmentation of left atrial (LA) scars from late gadolinium enhanced CMR images is a crucial step for atrial fibrillation (AF) recurrence analysis. However, delineating LA scars is tedious and error-prone due to the variation of scar shapes. In this work, we propose a boundary-aware LA scar segmentation network, which is composed of two branches to segment LA and LA scars, respectively. We explore the inherent spatial relationship between LA and LA scars. By introducing a Sobel fusion module between the two segmentation branches, the spatial information of LA boundaries can be propagated from the LA branch to the scar branch. Thus, LA scar segmentation can be performed condition on the LA boundaries regions. In our experiments, 40 labeled images were used to train the proposed network, and the remaining 20 labeled images were used for evaluation. The network achieved an average Dice score of 0.608 for LA scar segmentation.
4. Dr.Huang-Yu Yang - Chang Gung Kidney Research Center
Dr.Huang-Yu Yang. PROFESSIONAL POST. Attending physician in Department of Nephrology. Education. 1991-1998 M.D., Taipei Medical University.
PROFESSIONAL POST
5. Research – The Huang Laboratory - Pathology Labs
... Huang CC, Yang JM†, Huang CH†. Reconstructing signaling networks using ... SCAR/WAVE complex. It was not clear how these events were triggered in the ...
Our lab is interested in understanding the structure, dynamics, and functions of the signaling network involving receptor tyrosine kinases (RTKs) and their downstream effectors such Ras, PI3K and MAPK/ERK pathways. We use an interdisciplinary approach including fluorescent live cell imaging, genetics, synthetic biology, optogenetics, and mathematical modeling to uncover the mechanisms and properties of the network in cell biology, as well as in vivo models and patient samples to investigate the implications in cancer treatment.
6. Liang Huang - Google Scholar
L Huang, L Yang, K Yang. Physical Review E 73 (3), 036102, 2006. 55, 2006. Transmission and scarring in graphene quantum dots. L Huang, YC Lai, DK Ferry, R Akis ...
See AlsoJames Dutcher 2014 MovieLanzhou University - Cited by 2,633 - nonlinear science - graphene - quantum chaos
7. M2 microglial small extracellular vesicles reduce glial scar formation ...
... Huang S, Wang Y, Tang Y, Shen F, Tian HL, Yang GY, Zhang Z. M2 microglial small extracellular vesicles reduce glial scar formation via the miR-124/STAT3 ...
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8. Liang Huang 's homepage at ICPCS, LanZhou University
Huang, "Quantization condition of scarring states in complex soft-wall ... Yang, and L. Huang, "Observation of alternately localized Faraday waves in a ...
Welcome to Liang Huang 's homepage at ICPCS, LanZhou University
9. Diagnostic value of transvaginal three-dimensional ultrasound ...
... scar pregnancy. Liangyan Shi1#, Lijuan Huang1,2#, Lu Liu1, Xiaohong Yang3, Dongmei Yao1, Dejun Chen1, Jun Xiong1, Jie Duan1. 1 Department of Gynecology , ...
Diagnostic value of transvaginal three-dimensional ultrasound combined with color Doppler ultrasound for early cesarean scar pregnancy
10. [PDF] Relativistic quantum scars. - Semantic Scholar
Quantum chaotic scattering in graphene systems · Rui YangLiang HuangY. LaiC. Grebogi. Physics. 2011. We investigate the transport fluctuations in both non ...
11. [PDF] Representing the Chinese Cultural Revolution in Scar Lit - ERA
Huang Zhigang's dissertation Chinese scar literature on the Cultural ... the former article, Yang classifies scar literature as a stage of “the repressive.
